Taking Hydrochlorothiazide with alcohol may have additive effects in lowering blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.

Enace D 5 mg/12.5 mg Tablet is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

Enace D 5 mg/12.5 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.

Enace D 5 mg/12.5 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

Enace D 5 mg/12.5 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Enace D 5 mg/12.5 mg Tablet may be needed. Please consult your doctor.Regular monitoring of blood pressure, kidney function test, and potassium levels is recommended while you are taking this medicine.

Enace D 5 mg/12.5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Enace D 5 mg/12.5 mg Tablet may be needed. Please consult your doctor.